Kernel Metadata Declaration — on demand
ISO 26324 asks a DOI Registration Agency to produce a Kernel Metadata Declaration for every DOI it issues. Give any DOI: its public record becomes a record in the Smart Scholars DOI Metadata Format 1.0, checked against every rule, and declared as the Kernel XML.
✓ Meets every rule of the format
The record below is complete and every controlled value is a DOI Attribute Value Set 2.3 spelling. The Declaration on the right follows DOIMetadataKernel.xsd element by element.
What the DOI identifies
Inhibition of Proliferation of K-562 Human Blood Cancer Cell Due To Opuntia Elatior Fruit Extract
10.46243/jst.2021.v06.i04.pp32-38 · JournalArticle — an article in a journal · Digital · Visual · Language · en
Published 2021-07-14
Part of Journal of Science & Technology · ISSN 2456-5660 · vol. 06 · no. 04 · pp. 32–38
Principal agents
- Chirag U. Narayankar (author → Author)
- M. Mane (author → Author)
- R. Patil (author → Author)
- Longman Publishers (publisher → Publisher)
Also in the record, outside the Kernel: the abstract, the licence, 4 links, 30 references. Source: Crossref (member 25296), registered 2026-09-08, last deposited 2026-09-20.
System metadata — ISO 26324:2025, Annex B · DOI Handbook 10.1
Each element by the standard's name and the Handbook's (in grey), read off the record.
| DOI Name DOI name | 10.46243/jst.2021.v06.i04.pp32-38 |
| Referent Type referentType | Creation |
| Referent Sub-Type referentSubType | JournalArticle — an article in a journal |
| Referent Name(s) referentName(s) | Inhibition of Proliferation of K-562 Human Blood Cancer Cell Due To Opuntia Elatior Fruit Extract (PrincipalTitle, en) |
| Basic Metadata basicMetadata | author: Chirag U. Narayankar author: M. Mane author: R. Patil publisher: Longman Publishers published: 2021-07-14 part of: Journal of Science & Technology · ISSN 2456-5660 · vol. 06 · no. 04 · pp. 32–38 language: en form: Digital · Visual · Language |
| Referent Identifier(s) alternateIdentifier(s) | none besides the DOI |
| Registration Authority registrationAuthorityCode | Crossref — issued by Crossref (member 25296); held here as a copy |
| Created Date issueDate | 2026-09-08 |
| relatedIdentifiers | none needed — the descriptive metadata is in this record |
The record
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"doi": "10.46243/jst.2021.v06.i04.pp32-38",
"referent": "Creation",
"type": "JournalArticle",
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"modes": [
"Visual"
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"characters": [
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"type": "PrincipalTitle",
"lang": "en"
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"identifiers": [
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}
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"agents": [
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{
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"family": "R. Patil"
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{
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"name": {
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"dates": {
"published": "2021-07-14",
"date_type": "PublicationDate",
"online": "2021-07-14"
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"volume": "06",
"issue": "04",
"pages": {
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},
"links": [
{
"url": "https://www.jst.org.in/index.php/pub/article/view/433",
"return_type": "text/html",
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},
{
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"purpose": "text-mining",
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{
"url": "https://www.jst.org.in/index.php/pub/article/download/433/2921",
"purpose": "text-mining",
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{
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"purpose": "similarity-checking"
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"abstract": {
"value": "The ethanolic extract of Opuntia elatior was studied for anticancer potential against human blood cancer cell line K-562. The cytotoxicity of ethanolic extract was analyzed, using MTT assay and flow cytometric analysis. It was noticed that IC50 value of Opunria elatior curde extract was 74.32 µl/ml showing its cytotoxicity in the human blood cancer cell line by using MTT assay. The flow cytometry evaluation exhibits cell arrested in G2/M and S phases. Cell arrested due to Opuntia elatior extract shows higher than positive control Cisplatin. Thus Opuntia elatior fruit extract might be used as potent source of anticancerous compound against human blood cancer",
"lang": "en"
},
"license": {
"url": "https://creativecommons.org/licenses/by/4.0/",
"start": "2021-07-14",
"applies_to": "vor"
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"unstructured": "Aziz, A., Taha H., Mohebali N., Chung Y. L., Ismail N. H., Bakar M. Z. A. and Yusof F. Z. M., 2016. Anti-Cancer Potential of Pseuduvaria Macrophylla in Human Cancer Cell lines. Journal of Advanced Research in Applied Sciences and Engineering Technology. 4 (1), 1- 11"
},
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"key": "ref2",
"doi": "10.1107/s2053229617018551",
"unstructured": "Bhat S. S., Revankar V. K., Kumbar V., Bhat K. and Kawade V. A., 2018. Synthesis, crystal structure and biological properties of a cisdichloridobis (diimine)copper(II) complex. Acta Cryst. 74, 1-6"
},
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"key": "ref3",
"doi": "10.1007/s12033-010-9321-2",
"unstructured": "Baguley B.C., 2010. Multiple drug resistance mechanisms in cancer. Mol. Biotechnol. 46, 308- 316"
},
{
"key": "ref4",
"doi": "10.1002/jcp.22963",
"unstructured": "Chen Y. J. and L. S. Chang., 2011. Arecoline-Induced Death of Human Leukemia K562 Cells is Associated with Surface Up-Modulation of TNFR2. Journal of Cellular Physiology. 227, 2240–2251"
},
{
"key": "ref5",
"doi": "10.3390/molecules190914879",
"unstructured": "El-Mostafa K., El-Kharrassi Y., Badreddine A., Andreoletti P., Vamecq J., El-Kebbaj M.S., Latruffe N., Lizard G., Nasser B., Cherkaoui-Malki M., 2014. Nopal cactus (Opuntia ficus-indica) as a source of bioactive compounds for nutrition, health and disease. Molecules. 19 (4), 14879-91"
},
{
"key": "ref6",
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"unstructured": "Ertekin T., Bozkurt O., Eroz R., Nisari M., Bircan D., Nisari M., Unur E., 2016. May argyrophilic nucleolar organizing region-associated protein synthesis be used for selecting the most reliable dose of drugs such as rhamnetin in cancer treatments?. Bratisl Med J. 117 (11), 653–658"
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"key": "ref7",
"doi": "10.1016/j.imr.2017.01.004",
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{
"key": "ref8",
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},
{
"key": "ref9",
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"unstructured": "Gupta R. S., Murray W. and Gupta R., 1988. Cross resistance pattern towards anticancer drugs of a human carcinoma multidrug-resistant cell line. Br. J. Cancer. 58, 441-447"
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{
"key": "ref11",
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{
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},
{
"key": "ref13",
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{
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{
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{
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{
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{
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{
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{
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}
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"record": {
"registrant": "Longman Publishers",
"registered": "2026-09-08",
"updated": "2026-09-20",
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}The Kernel Metadata Declaration
DOIMetadataKernel.xsd · namespace http://www.doi.org/2010/DOISchema · Attribute Value Sets 2.3 · draft — the agency's DOI name is filled in on accreditation
<?xml version="1.0" encoding="UTF-8"?>
<!-- DRAFT declaration: Smart Scholars is not yet a DOI Registration Agency. registrationAgencyDoiName is a marker (10.0/ is no RA's prefix) and is filled in on accreditation. -->
<kernelMetadata xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.doi.org/2010/DOISchema https://www.doi.org/doi_schemas/DOIMetadataKernel.xsd" xmlns="http://www.doi.org/2010/DOISchema">
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<issueDate>2026-10-04</issueDate>
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<referentCreation>
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